One-liners we keep looking up. Add yours.
# in-place edit with backup perl -pi.bak -e 's/foo/bar/g' *.conf
# print lines 10 to 20 perl -ne 'print if 10..20' file
# sum a column
perl -lane '$s += $F[2]; END { print $s }' data.txt
# remove duplicate lines, keep order
perl -ne 'print unless $seen{$_}++' file
# convert DOS line endings perl -pi -e 's/\r\n/\n/' file.txt
# print the longest line
perl -ne '$l = $_ if length > length $l; END { print $l }' file
# count occurrences of each word
perl -lne 'for (split) { $c{lc $_}++ } END { print "$c{$_}\t$_" for sort { $c{$b} <=> $c{$a} } keys %c }' file
# random line perl -e 'srand; rand($.) < 1 && ($line = $_) while <>; print $line' file
# extract email addresses
perl -wne 'while (/[\w.+-]+@[\w-]+\.[\w.-]+/g) { print "$&\n" }' *.txt
Notes:
See also the Camel book chapter 19, and perldoc perlrun.